The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. Reviewed-Annotation score: -Experimental evidence at protein level i. SIGNOR curated interactions. Even if new antitubercular drugs are currently being developed, the rapid emergence and spread of drug-resistant strain remain a severe challenge. O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids (PubMed:20947662, PubMed:26169044). CASD1 subfamily. CIViC Summary ,
CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Diseases associated with CASD1 include Citrullinemia, Type Ii, Neonatal-Onset and Dystonia. Cistromic (ChIP-Seq) regulation report from, Genes around CASD1 on UCSC Golden Path with, CASD1 Gene in genomic location: bands according to
Summary Other designations. Sequence=AAB69978.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB15028.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=BAB15163.1; Type=Erroneous initiation; Note=Truncated N-terminus. Tocris Summary ,
SSGCID Block displays entry for this in Seattle Structural Genomics Center for Infectious Diseases. Sidebar on the left display quick links for easy access to other resources. gene expression, shRNA knockdown, CRISPR), VectorBuilder Viral vectors for CASD1 (ie. WormBase is supported by grant #U24 HG002223 from the National Human Genome Research Institute at the US National Institutes of Health, the UK Medical Research Council and the UK Biotechnology and Biological Sciences Research Council. Pseudomonas aeruginosa (strain UCBPP-PA14) Status. WormBase is an international consortium of biologists and computer scientists… Find out more, Start here to access encyclopedic information about the worm genome and its genes, proteins, and other encoded features… Find out more, Come explore WormBase's complex collection of information with a variety of bioinformatic tools and more… Find out more, WormBase provides a large number of precomputed files to facilitate downstream analysis… Find out more, Come join and connect with worm experts online and beyond… Find out more, We've created different user guides for distinct interests and experience levels… Find out more, WormBase is supported by grant #U24 HG002223 from the, UK Biotechnology and Biological Sciences Research Council. If no entry is available user can submit request through their website. CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CASD1 is a sialate O-acetyltransferase and serves as key enzyme in the biosynthesis of 9-O-acetylated … Genes above this line are annotated as required for growth on cholesterol. Ensembl, locations according to GeneLoc
Schubert et al., 2015 Cell Host Microbe. Structure and Domains Block include UniProt entry links, PDB and PM Portal entries if available and Subcellular localization information. This includes the CRISPR system of adaptive immunity. lentivirus, AAV, adenovirus), VectorBuilder Virus packaging for CASD1 (ie. Other users need a Commercial license. Free for academic non-profit institutions. Statistical significance was determined by t-test. This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 1,100.00 and 2,300.00 for bicluster_0340 and 590.00 and 780.00 for bicluster_0341 respectively. CRISPR loci are composed of short, palindromic repeats that occur at regular intervals composed of alternate CRISPR repeats and variable CRISPR spacers between 24-48 nucleotides long. 9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide. PharmGKB "VIP" Summary ,
Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus-dystonia syndrome. Diseases associated with CASD1 include Citrullinemia, Type Ii, Neonatal-Onset and Dystonia . This gene was present in the common ancestor of eukaryotes.