CTL was rebranded as Celixir in 2016. Founded in 2015, Freeline Therapeutics aims to treat chronic diseases with gene therapy. Three of them are being tested in pivotal clinical trials and could soon receive approval. Cell Medica develops next-generation CAR-T cell cancer therapy that engineers a type of immune cell called natural killer T (NKT) cells, instead of the T cells commonly used for this type of treatment. We use cookies to improve our site experience. While GSK had only managed to sell the therapy once, in 2018 Orchard reported €1.9M in sales from Strimvelis in Europe. Today, we are a leader in engineered T cell therapy, which has changed the paradigm of cancer treatment as one of the biggest breakthroughs in medicine since the introduction of combination chemotherapy more than 60 years ago. The company aims to reduce the life-threatening side effects of this kind of treatment by killing cancer cells without affecting the healthy T cells required to protect the body from infections and other external threats. Cell and gene therapies continue to progress towards large scale commercialisation to add to the therapies already approved for use. Virion Biotherapeutics is developing ‘universal antivirals’ for respiratory viruses that cause colds and flu. that can better infiltrate and kill solid tumors. 12th Floor Tower Wing, Guy’s Hospital,Great Maze Pond, London SE1 9RT, Working with a leading UK cell and gene therapy company on its flagship product. We make it our job to stay at the forefront of the latest innovations in cell and gene therapies, so that we're ready to help, whenever you might need us. Preliminary results in healthy volunteers seem to indicate the drug has an effect on the nervous system that could help patients with schizophrenia. The benefits of this collaboration included development of new expertise at the Cell and Gene Therapy Catapult which can be used again. In recent years, the city has seen big acquisitions of biotech companies such as Nightstar Therapeutics or Heptares. GammaDelta Therapeutics develops cell therapies for cancer using a rare type of immune T cells called gamma delta T cells that can better infiltrate and kill solid tumors. CELL AND GENE THERAPY CATAPULT - Free company information from Companies House including registered office address, filing history, accounts, annual return, officers, charges, business activity This year’s agenda includes a mix of on-demand content that will be released each morning in addition to two live-streaming panels each day at 8am PT and 12pm PT. Of the many firms based in the city, these are the 10 biotech companies in London you need to know. See how we help companies and researchers overcome industrialisation challenges and accelerate their development. The Cell and Gene Therapy Catapult works with Innovate UK. After a. in 2018, the company is now valued at over €1B. The company aims to use the ability of NKT cells to better infiltrate solid tumors to extend the use of this kind of therapy beyond blood cancer. With the Cell and Gene Therapy Catapult playing a key role in advancing the, development of these therapies, this will not only bring concrete benefits to patients but will also allow the UK sector to compete globally.”. The annual ‘Top Cell and Gene Therapy Biotechs to Watch’ e-book examines 15 of the world’s leading cell and gene therapy biotechnology companies, providing you with an at-a-glance view plus more detailed information on how their pipelines are developing. The company aims to reduce the life-threatening side effects of this kind of treatment by killing cancer cells without affecting the healthy T cells required to protect the body from infections and other external threats.